By shifting these coordinates, we simulated optic disc center displacement in the RNFL thickness map without requiring repeat scanning. Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) provides coordinate information of the optic disc center location in printout results. The purpose of this study is to investigate the effect of optic disc center displacement on RNFL measurement. Potential displacement of the optic disc center may affect every measurement in the 200 x 200 scan points of a RNFL thickness map, as well as in a 3.46-mm-diameter circumpapillary RNFL measurement. Because the optic disc center is calculated using the optic disc margin, error may also be incorporated in the optic disc center location. In previous studies using SD-OCT, the prevalence of optic disc margin detection errors was reported to range from 0.5 to 17.6%. However, automatic detection technique of optic disc in SD-OCT is not perfect. Due to these features, SD-OCT shows improved reproducibility of RNFL measurement compared to TD-OCT. Therefore, it consistently measures circumpapillary RNFL thickness along a 3.46-mm-diameter circle from the optic disc center. Spectral-domain OCT (SD-OCT) automatically delineates the optic disc margin and calculates the center of the optic disc. Accurate registration of circle scan is essential for measurement reproducibility and longitudinal examination. Due to the influence of eye motion and manually controlled circle placement, it is difficult to ensure consistent scan location in time-domain optical coherence tomography (TD-OCT). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.Īccurate measurement of retinal nerve fiber layer (RNFL) thickness is an important component in the diagnosis and management of glaucoma. ![]() This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the paper.įunding: This study was supported by the National Research Foundation of Korea (NRF), which is funded by the Ministry of Education, Science, and Technology (no. Received: JAccepted: OctoPublished: October 26, 2016Ĭopyright: © 2016 Shin et al. PLoS ONE 11(10):Įditor: Andrew Anderson, The University of Melbourne, AUSTRALIA (2016) The Effect of Optic Disc Center Displacement on Retinal Nerve Fiber Layer Measurement Determined by Spectral Domain Optical Coherence Tomography. 2013 131:107–9.Citation: Shin JW, Shin YU, Uhm KB, Sung KR, Kang MH, Cho HY, et al. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images. Shelton JB, Digre KB, Gilman J, Warner JEA, Katz BJ. Clinical features, imaging, and natural history of myelinated retinal nerve fiber layer. Acquired myelinated nerve fibers in association with optic disk drusen. ![]() 2021 46:1406–13.ĭuval R, Hammamji K, Aroichane M, Michaud JL, Ospina LH. Prevalence and clinical characteristics of myelinated retinal nerve Fibres in a Chinese teleophthalmology system. Prevalence and associations of myelinated retinal nerve fibers: results from the populationbased Gutenberg health study.
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